2015年12月31日星期四

Elderly kidney failure how else?

Elderly kidney failure how else? Elderly suffering from the disease will be based on the symptoms for kidney failure treatment, but also for the disease complications should also be understood that in order to truly cure the disease.

(A) clinical symptoms

History is not typical elderly renal failure can not clear progression occult, clinical often fatigue, anorexia, nausea, vomiting and other gastrointestinal symptoms to seek treatment, severe mouth of urine, and even gastrointestinal bleeding. Poor, insomnia, difficulty concentrating are common psychiatric symptoms of early disease. Personality changes late disease: depression, memory loss, an error of judgment, indifferent reaction to the outside world. Uremia often have mental disorders, hallucinations, coma, increased neuromuscular excitability often arise, including hiccups, muscle spasms. Renal failure, often late peripheral neuropathy, lower extremity deep section appears strange feeling and was ant-aliasing or tingling, called restless leg syndrome.

(B) complications

Hypertension is a common complication of renal failure, if not timely and effective control of blood pressure can also increase renal damage, creating a vicious cycle. Other cardiovascular complications include pericarditis, cardiomyopathy, heart failure. About 50% of the patients died and cardiovascular complications. Elderly often accompanied by anemia, renal failure, anemia is associated with symptoms of uremia. Anemia can make heart failure and angina symptoms worse. Anemia related to kidney mechanism is controversial, in addition to a variety of factors cause kidney produce insufficient erythropoietin factor, the uremic plasma of some toxic substances also interfere with erythropoiesis and metabolism. Generally considered to be caused by multiple factors obstacle. Suffering from the disease can occur when water and electrolyte imbalance and metabolic disorders, hyponatremia, hyperkalemia, calcium and phosphorus metabolism imbalance (renal dystrophy syndrome), low blood sugar and high blood sugar and so on, if you can not get timely treatment It can be a cause of death of the patient.

Above for the elderly renal failure related content to do a presentation, hoping to help the elderly. There are a variety of clinical symptoms of the disease, but also a lot of complications, so the treatment method to be correct.


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Chronic renal failure (cell therapy) clinical manifestations?

Early chronic renal failure, most patients have no symptoms, blood chemistry abnormalities not evident, showing only hypertension, proteinuria and serum uric acid levels increased slightly. Such as chronic renal failure continues to progress, it can cause pathological changes in various systems. Gastrointestinal symptoms (loss of appetite, nausea, vomiting, gastritis, bad taste) common, often late gastrointestinal ulcers and bleeding. See cardiovascular symptoms of hypertension, heart failure, pericarditis. The skin may become brown, sometimes forming uremic frost, itching. BUN, creatinine increased plasma sodium may be normal or reduced. Acidosis often moderate, serum COz content of 15 ~ 20mmol / L. Normal or moderately increased serum potassium, common hypocalcemia and hyperphosphatemia and anemia. Specifically: your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

(1) Water metabolism disorders

Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer! Chronic renal failure due to different causes, reduced ability for water regulation, but the clinical manifestations vary, such as interstitial damage mainly patients include chronic pyelonephritis, less water retention See, often diluted urine, chronic glomerulonephritis is easy oliguria and water retention.

Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

(2) electrolyte metabolism

Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

1) Sodium: Chronic renal failure patients generally be normal salt intake does not appear sodium retention, thus unless there is sodium retention, not all sodium restriction. Some tubular damage mainly in chronic renal failure patients, such as chronic pyelonephritis, renal cysts, analgesic nephropathy, since the kidneys can not absorb enough sodium back, is prone to hyponatremia. Chronic renal failure due to poor kidney adaptability, a sudden increase in sodium load and reducing sodium intake will have an adverse effect on the kidneys.

2) Potassium: Potassium balance also depends on renal tubular function, a non-end-stage chronic renal failure patients, serum potassium were normal, because of vomiting, diarrhea, and potassium supplement potassium and other factors also appear insufficient; terminally ill, Sometimes potassium will rise, mainly seen oliguria and metabolic acidosis and high potassium intake of drugs, food, etc., since the potassium levels within cells was significantly higher than normal cells, up to 150mmol / L, while its part to it is easy to make when a sharp rise in extracellular potassium outside the cell transfer.

3) Calcium, phosphorus: chronic renal failure patients prone to low blood calcium, but its slow, clinical manifestations obvious. Chronic renal insufficiency GFR decline approaching normal 1/5, phosphorus levels rise, this time by the parathyroid hormone (PTH) regulate the reactivity of renal tubular function decreased, so that elevated phosphorus and parathyroid gonadotropin secretion of a vicious circle. It appears hypocalcemia and hyperphosphatemia.

4) Magnesium: When the glomerular filtration rate of less than 30ml / min, can occur hypermagnesemia. Serum magnesium concentrations higher than 1.64mmol / L (> 4mg / dl), it can cause drowsiness, loss of appetite, speech disorders. Higher than 2.88mmol / L (> 7mg / dl), drowsiness, blood pressure, bradycardia, atrioventricular block or ventricular conduction block, tendon reflexes. Easy on the symptoms and the clinical symptoms of uremia itself overlap or confusion.

5) Aluminum: accumulate in the body is an important reason leading to osteomalacia and encephalopathy, blood dialysate water quality in the aluminum-containing more long-term dialysis can cause an increase in aluminum content in brain tissue, dementia symptoms.

(3) acid base balance

When the glomerular filtration rate of less than 20ml / min, began to metabolic acidosis.

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How stage chronic renal failure?

How stage chronic renal failure? Case of chronic renal failure stage is carried out? According to the severity of stage. Generally can be divided into four phases in clinical, each treatment is not the same.

Chronic renal failure refers to kidney disease or chronic kidney diseases involving the kidney caused by systemic loss, as well as a variety of clinical symptoms and the resulting metabolic disorders consisting syndrome. In a few cases, chronic renal failure may also be transformed from acute renal failure from. We will now be described with chronic renal failure in clinical staging. So as to obtain treatment for kidney failure.

(1) decompensated chronic renal failure (renal decrease of reserve capacity): patients without kidney failure symptoms. Serum creatinine <133 u m01 / L; GFR (glomerular filtration rate) 50-80 ml / min.

(2) chronic renal failure decompensation (azotemia): renal failure early, patients are usually no obvious symptoms, may have mild anemia, polyuria, and nocturia increased: serum creatinine> 133 μmol / L, but <450 μmol / L: GFR (glomerular filtration rate) 25-50 ml / min.

(3) chronic renal failure decompensation late (stage renal failure): anemia in patients with obvious, nocturia and water, electrolyte imbalance, and may have mild gastrointestinal, cardiovascular and central nervous system symptoms; serum creatinine It was significantly higher (approximately 450-707 u mol / L); GFR (glomerular filtration rate) 10-25 ml / min.

(4) end-stage chronic renal failure (uremia): advanced renal failure, renal failure and clinical manifestations of blood biochemical abnormalities have been very significant, uremia syndrome group, each severe symptoms, especially stomach intestinal, cardiovascular, and neurological symptoms more prominent. Water, electrolyte imbalance serious, often have significant metabolic acidosis, serum creatinine greater than 707 u mol / L: GFR (glomerular filtration rate) of less than 10 ml / min.

Stage chronic renal failure is helpful for the treatment, can make the appropriate treatment according to the disease in different periods. This species is more likely in early treatment, once inside there are some difficulties in the late treatment.

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How to prevent chronic renal failure (cell therapy)?

How to prevent chronic renal failure? Early prevention of chronic renal failure have increasingly attracted the attention of experts and scholars. Early prevention, also known as "primary prevention" refers to chronic renal failure before prevention starts. Early census includes kidney disease, kidney disease to kidney disease and may involve a positive control, in order to prevent the occurrence of chronic renal failure. Early measures to prevent chronic renal failure are: your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

(1) to strengthen follow-up: regular follow-up to delay the progression of renal failure is very good, there are plans to make the patient for treatment and receive guidance to help patients reduce or avoid aggravating renal incentives, such as drug-induced damage, caused by dehydration hypovolemia, hyperlipidemia, hypercalcemia, hypokalemia, urinary tract obstruction, infection, bleeding and so on. Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

(2) a reasonable diet: a lot of research and clinical observation experiments showed that slows down low protein and (or) low-phosphorus diet enables most patients with chronic renal failure process, even temporarily stop the progress of renal failure. Low-protein diet or combined with essential amino acids reduce chronic renal hyperfiltration state, help prevent progression of chronic renal failure. The main measures to control hyperphosphatemia is low phosphorus diet, such as taking phosphate binders. Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

(3) control of blood pressure: renovascular hypertension or primary control, can prevent progression of glomerular sclerosis. The former is mainly controlled glomerular hyperperfusion, which rely mainly on the application of antihypertensive drugs. Control high blood pressure (or diabetic nephropathy) can be applied to small doses of angiotensin-converting enzyme inhibitors (captopril), can reduce glomerular pressure, relieve high filtration state. Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

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Renal failure (cell therapy) will be lethargy are the symptoms?

Why lethargy symptoms of renal failure? Symptoms of renal disease are not the same in different periods, in which there is a symptom, it is lethargy symptoms of kidney failure. But many people do not know the symptoms of kidney failure belongs to that period, so I want to look at aspects of this knowledge.

First we have to understand that it is divided into acute and chronic renal failure, renal failure progression rapid, usually due to insufficient renal blood supply (such as trauma or burn), renal function due to some factors that cause damage or obstruction It is hurt by the poison, causing kidney failure generation. The chronic renal failure was mainly due to long-term kidney disease, along with the time and the disease, decreased kidney function, resulting in renal failure.

After the illness should be treated, no matter what kind of disease, the patient must first maintain a good mood for treatment, the disease can be used for kidney failure and electrolyte balance disorder treatment methods, hypocalcemia and hyperphosphatemia kidney dysfunction, urinary excretion of phosphorus reduced, leading to elevated serum phosphorus. The combination of phosphorus and calcium from the intestinal discharge compensation, limiting the absorption of calcium, low albumin, when coupled with anorexia and kidney, as well as kidney illness after 1.25 (OH) 2D3 generated obstacles, etc., will reduce the calcium. Hyperphosphatemia and hypocalcemia stimulate the parathyroid glands, causing secondary hyperparathyroidism, leading to bone calcification disorders, which will produce rickets in young patients, adult patients with uremic osteodystrophy occurs.

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How to prevent renal failure (cell therapy)

If you are in hospital undergoing surgery or serious damage, the risk of renal failure at this time to further increase, to take some preventive measures according to their specific circumstances, common are: Your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

1) RDA. Daily intake of sugar compound requires at least about 100 grams, while the protein will be subject to certain restrictions. Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

2) daily intake and exhaust careful measurements recorded weighed daily requirements. Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

3) to monitor changes in blood pressure. Measuring blood pressure several times every day. Your question nephropathy experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

4) The blood will be tested regularly to monitor changes in the electrolyte.

5) the amount of liquid to maintain the balance, fluid volume at this time is carefully calculated and determined.

6) careful medication. Each of your medication will have been carefully compare and consideration to ensure that will not increase the burden on the kidneys. Medicine containing magnesium ions tend to be discontinued. Meanwhile, the dose of medication will be subject to certain adjustments, which may be different from normal people.


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What renal failure (cell therapy) is characterized?

What is characterized by kidney failure? Words for renal disease, patients should be promptly controlled to avoid deterioration develop into kidney failure. So on the issue of kidney failure characteristics, it is necessary to pay attention to patients with kidney disease who, through the characteristics of understanding, to better grasp the disease.

About kidney failure is characterized roughly divided into the following three types,

1, ischemic, this situation is in shock, trauma-induced early renal failure, glomerular no more change, proximal convoluted tubules degeneration, tubular epithelial cell cilia loss, severe renal tubular necrosis can occur, necrotic area surrounding inflammatory cell infiltration, distal convoluted tubule and collecting tube cavity expansion, there are tube lumen.

2, kidney toxin, through years of research found that nearly tubule epithelial cells were fused necrosis, necrotic cells and exudate filled lumen, severe damage to the small tube rupture. Distal tubule may also be involved, necrosis and degenerative changes. There are varying degrees of renal interstitial edema and inflammatory cell infiltration. Glomerular intact.

3, acute interstitial inflammation type, which is one of the features on kidney failure, usually because of an increase in kidney, renal interstitial edema, have cell infiltration and collagen fibers. Normal glomerular kidney restore normal or residual between fibrosis.

Experts also pointed out that renal failure in the elderly or have kidney disease, the pathological changes may not typical. In addition, the severity of pathological changes and clinical treatment of the kidney is also affected. Condition improved after treatment, the light lesions disappeared. Severe affected tissue can not be repaired, was interstitial fibrosis, scarring, belongs glomerular gradually shrinking, was hyalinization, resulting in varying degrees of persistent renal dysfunction.


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Renal failure (cell therapy) polyuria of complications are those?

Multi-stage renal failure, urinary complications are those? Under normal circumstances, a lot of patients with renal failure, polyuria want to know what are the complications of, by understanding, can enable patients to have a great future course of treatment help. Therefore, patients do not understand, it is necessary to find out.

Recently, many kidney failure patients in the consultation, the complications of renal failure polyuria is the question of what, for that matter Jingdong Sino-US Hospital experts to carry out the relevant knowledge to explain. For renal diseases, it generally has to go through polyuria, oliguria (or no urine period) and recovery of the three stages of development, with regard to renal failure polyuria in clinical complications, usually in the patient daily urine up 3000-5000ml, due to discharge large amounts of water and electrolytes, there may be dehydration, hypokalemia, hyponatremia, etc. If you do not replenish, patients can die from severe dehydration and electrolyte imbalance.

By understanding, we can be found in the urine of more than aware of the complications, the patient should also be aware oliguria, mainly infection, it is the most common and most serious one, more common in severe trauma, burns caused by high decomposition type renal failure. Cardiovascular system manifestations include cardiac arrhythmias, heart failure, pericarditis, hypertension. Nervous system and the performance of headache, drowsiness, muscle twitching, coma, seizures and so on. Nervous system and toxin retention in the body as well as water intoxication, electrolyte imbalance and acid-base balance disorders. Digestive manifestations of anorexia, nausea, Qu vomiting, abdominal distension, vomiting blood or blood in the stool, bleeding due to gastrointestinal mucosal erosion or ulceration caused by stress. Blood system due to the sharp decline in renal function, can reduce erythropoietin, causing anemia, but most are not serious. Small number of cases due to reduced clotting factor, may have bleeding tendencies. When kidney failure patients entered during the recovery period when the majority of patients with renal failure, renal function can be fully restored, a few patients can be left under varying degrees of renal impairment.


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Cold medicine can cause renal failure (cell therapy) it?

Cold medicine can cause kidney failure it? Cold is a normal thing, but it must have a lot of people do not know if the chaos taking cold medicine, then, is likely to cause kidney failure. So sick timely treatment is right, but to be drug fishes in a doctor's guidance.

Currently name of cold medicine are many, but most of its pharmaceutical ingredient similar role is similar. If two or more cold medicine while taking the equivalent of increasing the dose, the risk of adverse reactions will increase exponentially. Compound cold medicine containing acetaminophen as many as three dozen, some patients eager to relieve symptoms, self-medication with paracetamol inclusive of several anti-cold medicine, is likely to cause serious liver damage, as well as cold medicine may cause kidney failure such disease, so doctor is very important.

So after this issue, renal failure patients during illness, to ask the doctor, in drug treatment. At the same time can be selected for their main symptom of a drug, rather than eat a cold medicine, pain medication and to eat. Also ask the following four questions during the Qing medication, the medication should be when to start, what are the side effects of this medication? What need to avoid food, drink, medicine or taking medicine? If there is a forgotten dose, enteric-coated tablets, sustained release drug , capsules, dragees and other drugs in addition to the instructions license, but generally can not take crumble, crush and chew if these drugs will destroy the structure will not only reduce the efficacy, oral and gastric stimulation, some toxic side effects.

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Chinese medicine treatment of chronic renal failure can play what role?

Chinese medicine treatment of chronic renal failure can play what role? Chronic renal failure is caused by a primary glomerular disease, serious kidney damage, resulting in decreased renal function can not maintain the body's normal metabolic balance, hypertension, high blood pressure, proteinuria and other symptoms. If you can play through traditional Chinese medicine what effect?

Severe stage of kidney disease. Progression of renal damage in chronic renal failure is not an independent disease but a variety of causes of deterioration of end-stage performance. Causes of renal failure is the most common primary glomerular diseases; secondary glomerular diseases, such as how to treat diabetes, hypertension, systemic lupus erythematosus, allergic purpura, what is the cause of chronic renal failure ? Treatment of chronic renal failure have? chronic renal failure how to prevent it?

Chinese medicine is how the treatment of chronic renal failure? Usually the treatment of kidney disease, appear the most is the oral drug detoxification, mainly Ai Xite, Niaoduqing, oxidized starch, Shenshuaining, these drugs can play a role in detoxification, elimination of symptoms, but the root cause is still, and this is the main cause of recurrent disease, then how chronic renal failure should be treated?

According to scientific diet and treatment the patient's condition developed:

(A) generally use low-protein diet, but not to produce negative nitrogen balance principle. Should be given high-quality protein, such as eggs, dairy, fish, lean meat and so on. Limiting intake of vegetable protein. ② high-calorie, less than a day 125.5kJ / kg body weight. ③ vitamin supplements. ④ water intake should be, as the case may be, daily urine output in more than 1000ml. Nor edema should not water restrictions. ⑤ do not have too much salt restriction, because the sodium storage dysfunction, urine sodium loss. ⑥ oliguria should be strictly limited phosphorus potassium foods.

(B) the treatment of essential amino acids essential amino acids oral or intravenous fluid, adult daily 9-23g. Where the use of this method should not eat with non-essential amino acid-rich foods, and eating low amounts of high-quality protein (daily 0.3g / kg body weight), in order to promote the body's use of urea non-essential amino acids, and then the synthesis of human proteins and essential amino acids, thereby to reduce blood urea nitrogen purposes.

(C) Upon sodium expansion diuretic therapy that first-served sodium bicarbonate 3g / d, (such as patients who already Shuina Zhu slip, without first serving sodium bicarbonate), and then give furosemide, starting dosage is 100mg / d, quiet Note that daily urine output of about 2000ml, otherwise, doubling the speed of urine daily until it reaches far above the amount of urine, but the total daily dose of furosemide should not exceed 1000mg, such as furosemide every exceeds 200mg, should be added to the glucose solution within infusion.

(Iv) the application of vasoactive drugs dopamine 20mg, phentolamine 10mg added to 250ml of 5% glucose solution intravenously, drip 1ml / min, 1 day, a total of seven times. May improve renal blood flow, urine output increased, blood urea nitrogen discharged promote.

(E) Oral oxidized starch 20-40g / d, can gut a combination of urea and oxidized starch excreted, 1-2 weeks, blood urea nitrogen can be reduced by about 30%, because of dizziness, nausea, diarrhea Side effects, the current multi DASC (albumin oxidized starch coating formulation), the formulation minor side effects.

(Vi) rhubarb 10g, oysters 30g, dandelion 20g, decoction to 300ml, high enema 1-2 times a day, daily control in patients with diarrhea 3-4 times better promote fecal nitrogen excretion.

Chronic renal failure patients on drug side effects and treatment methods should be scientific and reasonable arrangement, and make the condition was stable control, in the treatment of immune complexes to remove kidney intrinsic cells to repair damaged main. The only way to stabilize the condition, which enable patients to return to normal life to go.

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What renal failure (cell therapy) is a common metabolic performance?

What common metabolic manifestations of renal failure?

Renal failure, also known as pre-uremia. Impairment of renal function has been quite serious, have been unable to maintain a stable internal environment of the body, patients prone to fatigue, weakness, difficulty concentrating and other symptoms can aggravate anemia significantly, nocturia, serum creatinine, blood urea nitrogen increased significantly, and often acidosis . This period is also called azotemia.

1, water, electrolyte and acid-base balance disorders: kidney regulate vital organs water, electrolyte and acid-base balance, and its damage, can directly affect the normal conduct of these links, causing a series of clinical manifestations.

(L) Acidosis: mild acidosis can no clinical manifestations. When the carbon dioxide combining power less than 15 mmol / liter, it can be expressed as breathing deepened to speed, loss of appetite, nausea, vomiting, weakness, irritability, severe disturbance of consciousness, and coma.

(2) dehydration and edema: edema can occur in patients with renal failure, dehydration can also occur. This is due to renal tubular dysfunction, concentration loss of function, even without drinking water, but also can emit large amounts of dilute urine, the results lead to thirst, urine dehydration performance, as you will not pay attention to supplement reduced renal blood flow, renal ischemia, accelerate kidney damage, so water in this case more important than medication. On the other hand, renal excretion poor, overload if water intake, water and no discharge, retention in the body, manifested oliguria, weight gain, edema, renal vascular swelling affecting renal blood flow, but also can aggravate kidney damage. Therefore, the weight should be measured daily, recording and other additional 24 hours urine excretion, which is an important observation index.

(3) the sodium, potassium, Change: Cause of hyponatremia is renal tubular sodium reabsorption dysfunction, but also with long-term low-salt diet, diuretics and diarrhea and so on. High sodium is due to uremia more urine without edema, and thus did not restrict salt intake, sodium retention and beyond renal natriuresis load. Can occur weight gain, edema, and even cause decreased urine output. We should always observe whether the fatigue, drowsiness, tendon reflexes and other low-sodium performance and the performance of the aforementioned high sodium should regularly review the content of various electrolytes in the blood, in order to adjust. Oliguria and long-term use of potassium-sparing diuretics are the most common cause of hyperkalemia causes. In addition uremic patients because excretory function decline, and due to the poor appetite, calorie intake, leading to tissue decomposition accelerated release of large amounts of potassium, combined with acidosis, increased sodium kidney exchange, exchange potassium and sodium reduction and other reasons, can cause a sudden increase in potassium, myocardial suppression appears on clinical manifestations, such as low heart sounds, slow heart rate, heart rhythm disorders and even arrest; also common symptoms of skeletal muscles, such as numbness, fatigue, weakness and numbness, paralysis, symptoms often caused by development of lower extremity upwards; fainting may occur and consciousness disorders; respiratory muscle can sometimes suppress, resulting in respiratory arrest. The occurrence of hypokalemia include two aspects, one due to the body water retention appears dilutive hypokalemia, hypokalemia performance time there, and the amount of potassium and a lot, mainly due to the re-distribution of potassium in the body; the other On the one hand due to the intake of too little, vomiting, diarrhea, loss, and loss caused by the lack of a diuretic potassium in, there really hypokalemia. In addition to the performance of hypokalemia paralysis gastrointestinal symptoms (such as bloating, bowel sounds decreased), the remaining manifestations and symptoms similar to hyperkalemia.

2, poisons and metabolites accumulated symptoms caused by:

(1) the hematopoietic system: chronic renal failure patients have anemia of varying severity, and more from chronic malnutrition, erythropoietin reducing and due to hemolysis. Renal failure patients have bleeding tendencies, manifested as subcutaneous bleeding, bruising, bleeding gums, epistaxis, severe gastrointestinal bleeding and death can occur. Additionally, you can have abnormal white blood cells, as "uremic toxins" role, so that the formation and function of white blood cells are obstacles, WBC decrease (mainly lymphocytes decreased production), neutrophil chemotaxis, phagocytosis and the ability to kill bacteria also decreased.

(2) the performance of the digestive system: Digestive System performance is the earliest and one of the most common manifestations, mainly anorexia, dyspepsia. Severe cases may have glossitis, oral erosion. May have vomiting, bloody diarrhea if peptic ulcer involving the blood vessels.

(3) Respiratory system: respiratory system generally arise when there is difficulty in breathing acidosis, but also by generating bronchitis, pneumonia and pleurisy and other symptoms of uremia.

(4) the cardiovascular system: common are hypertension, myocarditis and pericarditis uremia, a variety of arrhythmias and heart failure.

(5) The skeletal system: Because calcium and phosphorus metabolism, may appear osteoporosis, osteomalacia or osteitis inflammation and pain pseudo fractures.

(6) Skin manifestations: it can be manifested as skin pale, dry, itching and "urea cream."

(7) neuropsychiatric symptoms: central manifestations unresponsive, depression, irritability, agitation, convulsions, lethargy and coma. Peripheral lesions showed the performance of peripheral nerve degeneration, skin allergies, burning, limb weakness and movement disorder.

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Renal failure occurs nonoliguric performance

Renal failure refers to a sudden and sharp decline in renal function in the short term and cause the clinical syndrome. Mainly as a significant reduction in urine output or no urine, azotemia, metabolic acidosis, hyperkalemia, edema, and other multi-organ system symptoms and biochemical abnormalities.

Nonoliguric acute tubular necrosis is no little or no urine manifestations of acute tubular necrosis, average daily urine volume exceeds 1000ml. Nonoliguric risk factors and oliguric different, the former is due to renal aminoglycoside antibiotics and toxic substances caused by contrast agents, and oliguric more from the surgery, leading to renal ischemia. Nonoliguric laboratory indicators were less urinary light pattern changes. Was isotonic urine, fewer urinary sodium content, the lower sodium excretion fraction, less than 1 percent, to a lesser extent elevated serum creatinine / renal function recovered rapidly nonoliguric merger, less disease and less urinary type who, mortality is also low, less need dialysis. But the fatality rate is still 26%, individual seriously ill patients still need dialysis. In recent years, non-oliguric acute renal failure incidence increased year by year, up to 70% -80%. Not only because of the increased awareness of the disease than in recent years due to increased use of aminoglycoside antibiotics, and drug-induced acute tubular necrosis multiple non-oliguric. In addition, early acute renal failure reasonable use of diuretics, dopamine and mannitol increased renal blood flow and urine scouring action is often the performance of non-oliguric.


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How to prevent chronic renal failure?

How to prevent chronic renal failure? Chronic renal failure is still a difficult to treat disease. Most treatments only delay the process of chronic renal failure, advanced to rely on dialysis and kidney transplantation. Patients often endure long-term illnesses, family medical costs and face unbearable pressure. Therefore prevention of chronic renal failure occurs is critical.

Chronic renal failure is a clinical syndrome, late in various kidney diseases, renal dysfunction, water and electrolyte imbalance, toxins can not be successfully excreted in urine, caused by systemic symptoms. So, for chronic renal failure How to prevent it? The key is good control of the primary disease.

Chronic renal failure is the most common primary diseases of chronic glomerulonephritis. Often the consequence of a variety of glomerular diseases. Such as acute glomerulonephritis, nephrotic syndrome. There are other chronic pyelonephritis, lupus nephritis, urolithiasis, diabetic nephropathy, hypertension, renal artery stenosis, poisoning kidney disease and so on.

It can be said of these may cause chronic renal failure disease should pay attention to, active treatment. Such as acute glomerulonephritis can occur at any age, but more common in children, the vast majority occurred after infection, especially after streptococcal infection, inflammation caused by glomerular immune system, the infection is more common in the respiratory tract infections, skin infections and scarlet fever. When this occurs after infection in addition to active treatment, they must also check the urine in 2-3 weeks. In the treatment of pyelonephritis sure to use really effective antibiotic treatment and foot treatment.

How to prevent chronic renal failure? In view of the kidney has a strong compensatory function, sometimes has been serious damage to the kidneys, kidney dysfunction, but in compensation, the kidney itself and the lack of pain nerves, some important information is sometimes overlooked cause adversely affected by illness. So, for the early detection of renal failure, when there is unexplained loss of appetite, nausea, vomiting, headache, insomnia, convulsions, edema, hypertension, anemia, bleeding, should go to hospital checkups.

In addition, regular visits to the hospital to check on how the body is an important factor in the prevention of chronic renal failure, can not suffer in silence in the face of disease, to believe in science and treatment of confidence.

For early detection of renal failure, when there is unexplained loss of appetite, nausea, vomiting, headache, insomnia, convulsions, edema, hypertension, anemia, bleeding, should order early detection of renal failure, when there is unexplained loss of appetite, nausea and vomiting , headache, insomnia, convulsions, edema, hypertension, anemia, bleeding, due approaching hospital checkups.

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What renal failure (cell therapy) symptoms

What are the symptoms of renal failure

What are the symptoms of kidney failure is? Treatment of renal failure and kidney failure What are the symptoms are related, many types of renal failure, according to its kind to determine what are the symptoms of kidney failure, types, symptoms will be different, Here are some of the symptoms of kidney failure is what?

What are the symptoms of kidney failure is? Early renal failure patients did not have any obvious symptoms manifested, renal abnormalities before the damage can only be found through clinical laboratory tests. Thus, the occurrence of early renal failure patients often do not know their own illness or that it can not be seriously, thus delaying the best time for treatment of renal failure.

What are the symptoms of mild to moderate renal failure: progression of kidney failure in patients with mild to severe hypertension, despite the blood and other body metabolic wastes such as urea increase, but clinically may only have mild symptoms. In this stage the patient, since the kidneys night can not be the same as the daily as to absorb moisture from urine and concentrated, and therefore, this stage renal failure patients, it may be more cases of nocturnal polyuria, resulting in a total of increase urine output. Conversely, due to the occurrence of renal failure patients, so the majority of renal fibrosis has occurred, the number of units remaining normal kidney rarely, kidneys can not discharge excess salt and water, which will make more liters of blood pressure high. Thus, both high blood pressure and kidney failure will form a vicious cycle chain, promote mutual hypertensive renal failure aggravated the patient's condition.

What are the symptoms of kidney failure in late stage renal failure in patients with hypertension whose disease has been increasing, the advanced stage, the patient blood in the body metabolic waste piled up, these of harmful substances will affect the patient's muscles, nerves, digestive tract, brain, skin and other major body systems, causing kidney failure in patients with hypertension there was a series of clinical symptoms, such as muscle twitching, muscle weakness, muscle cramps, hands and feet, needle-like pain, nausea, vomiting, loss of appetite decline, bad breath, anemia, weight loss, skin, brown, white powder skin surface, body itching, convulsions, and the like. At this point, patients with hypertension deteriorates developed into uremia, enormous difficulty and risk of post-treatment.

These knowledge explains what are the symptoms of kidney failure, kidney failure What are the symptoms of the disease to see if it belongs to which type, so as to determine what the symptoms of renal failure, when patients find themselves suffering from kidney failure, and do not pressure, is recommended in patients transplantation therapy using cell therapy, cell therapy transplant treatment effect is more obvious, cell therapy transplant can clearly control the disease progresses, delay the appearance of complications, as long as patients adhere to treatment, the combination of science nursing program, patients can stay away from dialysis.

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Chronic renal failure (cell therapy) caused respiratory complications

Nausea and vomiting in patients with chronic renal failure is digestive dysfunction performance. Because each patient varying severity, and thus the number and extent of nausea and vomiting is different, but many patients often clinically telling the doctor, morning nausea or vomiting increased, this is why? First, we should understand due to renal function failure, blood urea nitrogen increased, intestinal bacterial urease will break down urea into ammonia and stimulate the gastrointestinal mucosa and cause nausea, vomiting, nausea and vomiting and therefore an increased emphasis should and blood urea nitrogen. Renal failure, urine concentration dysfunction, nocturnal enuresis lot of patients, due to the massive loss of water at night, blood concentration, and thus the value of the relative increase in blood urea nitrogen morning, so early morning nausea and vomiting worse.

Chronic renal failure patients because of low internal environment disorders and immune function, and the occurrence of lung disease in vivo susceptible to pathogenic factors, mainly uremia, pulmonary edema, pleural effusion and so on.

(1) uremic lung: also known as uremic pulmonary edema, pneumonia, uremia. Its symptoms are mild, only the early symptoms of uremia caused by the gradual emergence of disease progression with mild to moderate cough, phlegm, and a small amount of breathing difficulties. When the development of interstitial fibrosis, dyspnea, and cyanosis increase. Small quantity is also an important symptom of hemoptysis. Be with cardiogenic pulmonary edema, pulmonary infection and pulmonary hemorrhage nephritic syndrome  phase identification.

(2) uremic pleural disease: incidence of 15% to 20%, pleural friction rub, chest pain or chest discomfort, shortness of breath or fever. Pleural friction rub lasted 1 to 15 days, may be associated with exudation. No relationship between blood urea nitrogen and bleed.

(3) pulmonary calcification: CRF often caused by soft tissue calcification, lung is the most common site. The clinical manifestations of chronic dyspnea or acute, sub-acute respiratory failure, chest X-ray may be completely normal. Stop calcium, parathyroid resection, low phosphorus diet, oral alumina and application of low calcium dialysate, increase the number or duration of dialysis can reverse calcification.

(4) uremic pulmonary edema: is one of the common acute nephrology. When CRF patients, especially oliguria, when no urine, such as the sudden appearance of severe dyspnea, orthopnea, with fear, a sense of suffocation, looking schungite, lips cyanosis, sweating, cough, expectoration, may be associated hemoptysis, and a lot of pink frothy sputum, lungs filled with rales symmetry and wheeze, heart rate, pulse weak and should be considered acute pulmonary edema.

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Chronic renal failure in the end is what kind of disease

Chronic renal failure in the end is what kind of disease

Chronic renal failure in the end is what kind of disease? Only to understand the knowledge, in order to obtain the right renal failure treatment options and let the patient a speedy recovery, it has a lot of symptoms, should also be noted that once a patient suffering renal failure, be sure to choose an effective method of treatment, if you choose inappropriate methods will increase the development of the disease, delay the best timing of treatment of patients, and therefore, the patient should be carefully chosen.

Chronic renal failure called chronic renal failure, renal units were destroyed due to the decrease, resulting in renal excretion of metabolic regulation and endocrine function is severely impaired and causing water and electrolytes, acid-base balance disorders a series of symptoms, signs and complications. Reason children with chronic renal failure in children is closely related to the age of the 1st detection of renal failure. 5 years of age with chronic renal failure often is the result of anatomical abnormalities, such as renal agenesis, renal dysplasia, urinary tract obstruction and other congenital malformations; 5 years after the later acquired chronic renal glomerular diseases such as glomerulonephritis, hemolytic-uremic syndrome or hereditary diseases such as Alport syndrome, cystic kidney disease based.

A variety of chronic kidney disease, with disease progression, progressive destruction of renal units, as well as the residual functional nephron insufficient to fully discharge metabolic wastes and internal environment constant, and thus the occurrence of urinary dysfunction and internal environment disorders, including metabolic waste and toxins retention, water, electrolyte and acid-base balance disorders, and accompanied by a series of clinical symptoms of the pathological process, known as chronic renal failure.

Watch for nausea, vomiting, diarrhea, lower limb must move often unbearable burning, itching, pain, convulsions and signs of bleeding and the like.

Physical examination: Note respiratory rate, depth, whether the ammonia odor, note the state of consciousness, the degree of anemia, with or without muscle twitching, dehydration, edema, oral ulcers, pericardial friction rub, pay attention to blood pressure and the presence of heart failure signs.

Chronic renal failure symptoms are many, it is a slow onset of the disease, if not treated in time will lead to uremia, once entered uremia stage, treatment will be very difficult, uremia we should not be unfamiliar word, uremic disease of cancer has the second-generation title, from here it is very difficult to see the good in order to complete a large extent uremia treatment of uremia dialysis can prolong the time interval, improve quality of life, and therefore chronic renal failure Patients should be careful not to come uremia this step.

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There are several stages of chronic renal failure development

There are several stages of chronic renal failure develop? You should understand that chronic renal failure is not an independent disease, but a variety of terminal kidney disease worsening outcome. Chronic renal failure is a disease category degree of deterioration of renal function, which determines the chronic renal failure have a variety of clinical symptoms.

There are several stages of chronic renal failure develop? This is a relatively long duration of renal failure have some relevance. The severity of the symptoms of chronic renal failure is directly related to the therapeutic effect of renal disease. Therefore, for renal failure patients, there must be mastered What are the symptoms of chronic renal failure, when the body when these symptoms can be timely medical treatment, the maximum limit of the control of the disease worsening, thus improving the quality of life of patients with kidney failure.

In different stages of chronic renal failure, patients will exhibit different clinical symptoms. There are several stages of chronic renal failure may develop specific instructions from the following aspects?:

First, patients with chronic renal failure, renal failure, there is no early symptoms, abnormal renal function only through laboratory tests found.

Second, check with mild to moderate chronic renal failure patients with chronic renal failure, blood urea nitrogen indicators of high, renal failure patients may have mild symptoms. At this stage, for renal failure patients, since the night as the kidneys can not absorb moisture from the urine is concentrated as it is normal and therefore the patient may need to urinate several times during the night, affect nighttime sleep. This is the urinary renal failure patients in the clinical, nocturia symptoms. Meanwhile, many patients with chronic renal failure associated with hypertension, edema symptoms, because their kidneys renal failure patients can not be discharged excess salt and water. High blood pressure can also lead to chronic renal failure patients with stroke and heart failure and other symptoms.

Third, chronic renal failure, end-stage chronic renal failure patients can not effectively control the disease, with the course of persistent, toxic substances in the blood of patients with kidney failure is increasing, so that the patient appeared frail, fatigue and other symptoms unresponsive. With the gradual increase in toxic substances, the patient may experience muscle and neurological symptoms, including muscle twitching, muscle weakness and spasms. In this case, the end of the patient's limbs, kidney failure will appear needle-like pain, and even some parts of the body may lose any feeling. Meanwhile, if high blood pressure or kidney failure in patients with toxic substances in the blood caused by abnormal brain dysfunction will lead to convulsions.

Resulting in renal failure patients body muscles, the nervous system in the body of excess accumulation of toxic substances at the same time, increasing the toxic substances can affect the patient's digestive system, causing nausea, vomiting, loss of appetite, oral mucosal inflammation and bad breath and other symptoms. These symptoms will further lead to chronic renal failure patients suffering from malnutrition and weight loss and other signs. Stage renal failure (uremia) patients often occur gastrointestinal ulcers and bleeding. Advanced chronic patients, symptoms of kidney failure may also occur in the skin system. Most patients with renal failure may become brown skin; when the renal failure patient is discharged with the sweat to form crystalline urea, patients will have skin itching symptoms.

There are several stages of chronic renal failure develop? There are a lot of patients do not understand is how the development of chronic renal failure, always feel good about themselves, there is nothing unusual phenomenon, therefore, often not timely treatment, can not be timely control the development of the disease, in fact, the disease has begun to deteriorate, and when the patient feels that there is and what is not when basically toward the uremia. Therefore, patients must pay serious attention, it relates to a future cure or even life-threatening.

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Elderly renal failure (cell therapy) What are the reasons

1, hypertensive renal parenchymal changes prevalence rate of hypertension in China from the 1950s to the 1990s, rose 5.11 percent to 11.88 percent, more than 60 years older prevalence of hypertension was 15% to 50%. Systemic hypertension can be transferred to the kidneys, resulting in a small kidney artery, particularly afferent arterioles and capillaries pellets damage, hardened. Hypertension group than in the control group of the same age GFR decreased significantly. Many experimental studies confirm that hypertension is an important factor to accelerate glomerular sclerosis, controlling high blood pressure can delay the progress of renal insufficiency.

2, diabetic nephropathy Diabetes is a common disease of the elderly, the course of 10 to 20 years, about 50 percent of people with diabetes clinical diabetic nephropathy occurred about 5% to 10% died of uremia. Have demonstrated reduction of glomerular filtration rate in diabetes more rapidly than non-diabetics, if accompanied by high blood pressure is more significant.

3, atherosclerotic renal vascular changes in the renal artery atherosclerosis is a part of systemic atherosclerosis. Often involving the abdominal aorta artery and renal arteries and trunk opening, lumen obstruction less than 50%, RBF, or GFR may change, along with blocking progress, renal blood flow, increased ipsilateral kidney renin release caused by increased blood pressure. And cholesterol diet can accelerate glomerular sclerosis, in high concentrations of lipoproteins, mesangial cells can capture lipids, resulting in mesangial cell proliferation, focal glomerulosclerosis.

4, lower urinary tract anatomical abnormalities and age-related anatomical abnormalities involving the urethra, male prostatic hypertrophy occur easily, can cause severe obstructive nephropathy, renal function loss. Women prone to pelvic relaxation, urinary incontinence, urinary tract infections, tumors and blocking one or both ureters or kidneys, affect renal function.

5, high-protein diet for many years more than the recommended daily dietary protein supply amount (RDA) 0.8g / kg, can lead to glomerular filtration and renal plasma flow increases into the plasma protein increased mesangial mesangial deposition , culminating in glomerulosclerosis. Limit protein diet can slow down the process of glomerular sclerosis.

6, drug-induced renal damage drugs cause kidney damage and the interaction between the drugs in elderly patients is very prominent. With the aging process, drug absorption, distribution, metabolism and excretion etc changed greatly enhanced role of the drug, prolonged duration of action, even at low blood concentration, the side effects can occur. Non-steroidal anti-inflammatory drugs, aminoglycoside antibiotics, analgesics and antidepressants can cause kidney damage.

7, other bacteria or viruses that cause immune damage, urinary tract infections and various types of kidney disease can aggravate elderly kidney damage. Heart failure, myocardial infarction, cardiac tamponade; bleeding, inadequate intake, vomiting, diarrhea, caused by low blood pressure; abuse of diuretics lead to renal hypoperfusion, renal ischemic injury will aggravate the renal function in elderly.

Various functions are elderly kidney with aging occur in varying degrees of changes due to the elderly by physiological aging and various pathological factors, it is still difficult to determine whether the mechanism of renal dysfunction caused by aging itself or due to a variety of diseases accumulated kidney damage.


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2015年12月28日星期一

Chronic renal failure (cell therapy) do inspections

Chronic renal failure do what check? Chronic renal disease need to be checked in a timely manner, which would allow the patient to determine the disease, thereby using the method for medical treatment. Thus, timely diagnosis is very important, not only for the treatment of post-helpful, but also allow the patient to a speedy recovery.

Experts said the medical profession in general in clinical, chronic renal failure inspection, it needs to be blood, urine, kidney function, blood biochemistry examination. This is chronic renal failure test items, the following is a detailed description, first aspect of blood, obviously anemia, normal cell anemia, normal or elevated white blood cell count. Platelets, small cell sedimentation rate accelerated. Followed by kidney function tests, the indicators are diminished. In addition, blood biochemistry, plasma albumin decreased, low blood calcium, phosphorus increased, blood potassium and sodium with the disease.

In addition to the above requirements, there is chronic renal failure patients the most important thing is to carry out routine urine examination, with the primary disease differ. Its common denominator is, ① reduce urine osmolality, much less in 450mOsm per kg, the weight low, more or less at 1.018, severe fixed between 1.010-1.012, as a nocturnal urine volume greater than the day when diluted urine concentration test various times were more than 1.020 specific gravity, specific gravity difference between the highest and lowest of less than 0.008. ② decreased urine output, more than 1000ml or less daily. ③ increased urinary protein excretion, glomerular late because the vast majority have been destroyed, but reduce urinary protein. ④ urinary sediment testing, can have varying amounts of red blood cells, white blood cells, epithelial cells and granular casts, waxy casts the most sense. And other items seized detection, X-ray KUB and angiography, isotope renography, renal scan, renal puncture biopsy testing, etiological diagnosis for help.

Under normal circumstances, after the diagnosis of chronic renal failure patients, effective treatment can be carried out, the current methods for the treatment of chronic renal disease, the patient can choose surgery, kidney transplant. Kidney transplantation is to implant a healthy kidney patients within the right lower quadrant of the iliac fossa. Because the right iliac fossa vascular shallow, easily connected with the new kidney vascular surgery. After more generally select internal iliac artery anastomosis, if the inner lumen of the right iliac artery atherosclerosis occurs, the lumen is small, insufficient blood flow after the fear, also can make the patient external iliac artery anastomosis, vascular anastomosis, release all resistance broken blood vessel forceps, pending new kidney blood supply is good, then sutured abdominal wall, to complete the operation. Kidney transplant kidney is not the exchange of new and old kidney.

Chronic renal failure do what check? Above is how chronic renal disease introduced checks, while its treatment methods were explained, in order to be able to better help this patient's disease.

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What renal failure (cell therapy) 4 is

What is kidney failure four? Under normal circumstances, there are a lot of people for kidney failure four is not very understanding, I do not know the disease this period is like. So, for that matter, we can turn to explain to you the first period from after the adoption of explanation, it will make the fourth this disease have a comprehensive understanding.

For chronic renal failure, it appears to many chronic diseases, including chronic glomerular nephritis, interstitial nephritis with chronic kidney, polycystic kidney disease, diabetic nephropathy, hypertensive renal body sclerosis, systemic lupus erythematosus , tuberculosis, gout. Before understanding kidney failure four, first we have to look at in addition to specific renal four, but also what are the period. Kidney failure

First to introduce the first period, when the renal function in patients with renal failure and only 50% of normal time, although this time worse than normal renal function, but still enough to maintain normal operation, check the values ​​on the performance of BUN or Cr cause still rising, clinical also asymptomatic, but has gradually destroy the kidneys. The second phase is renal insufficiency, renal function normally only about 25-50%, at this stage of renal function has been insufficient to maintain normal operation, characterized by mild azotemia, ie BUN and Cr microliters of blood, urine concentration ability to produce nocturia worse, mild anemia. If chronic renal failure patients vomiting, diarrhea, or restrict patients to drink or take drugs alienation protein, the patient is likely to be serious child of azotemia and acidosis. Then timely treatment is very important, otherwise when the disease is more serious, the treatment will bring inconvenience.

Through the above description, surely we already know four patients with kidney failure during the time period is already in the last.


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Renal failure (cell therapy) dialysis How effective?

How to renal dialysis effect? ​​Renal disease, clinically a very difficult to treat disease, usually after a lot of people suffering from this disease, mostly dialysis method of healing. So there may be a lot of people, knowledge in this area is not very understanding, it is necessary to look at the knowledge of this disease.

In fact, renal dialysis can be thinking points situation. In addition to dialysis is a kidney transplant can prolong life in patients with severe renal failure important and effective wrist. After all dialysis patients with renal failure can be analyzed when the body needs, the complication of the situation presented, as well as kidney function itself filtration rate and urine output, these indicators are all standard. If patients with renal failure urine can, filtration rate are within a certain range, complications have not yet presented, then be able to penetrate through micro-based traditional Chinese medicine therapies to delay treatment time. And if severe kidney deterioration, almost no urine, complications presented other important organs, then further delay dialysis time is unwise choice, may be life-threatening. Kidney failure

Under normal circumstances, there is little we may not know much about, and that is the process of chronic renal failure is divided into four, namely decompensated renal insufficiency, renal insufficiency decompensation, renal failure and renal failure on stage. Just have to renal failure patient's condition shall timely start of dialysis treatment, specifically, the opportunity is the best treatment that is beginning to reach the following indicators, serum creatinine ≥8mg / dl (≥707.2umol / L), serum creatinine elimination rate ≤10ml / min. Such timely positive treatment, can reduce the adverse repercussions this method after reducing toxin caused by a variety of complications, conducive to the rehabilitation of the body, so that patients adhere to good physical condition and a higher quality of life, and can reduce treatment The overall costs.

Above is renal dialysis method used for this disease introduction, I hope the above explanation can help patients with this disease.


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Elderly renal failure (cell therapy) knowledge

Knowledge about the elderly kidney failure, experts pointed out that for many elderly patients with renal disease who, because their children are not very understanding of this disease, so the process of treatment of the elderly, many places are doing unreasonable , giving treatment impact. Thus, for understanding in this regard, family members of patients is necessary to find out.

In recent years through the health survey found that in recent years with the growing aging population and a significant increase significantly the incidence of metabolic disease, renal failure etiology spectrum also undergone some degree of change, compared with the proportion of secondary nephropathy in the past it has been significantly increased. Elderly patients with renal failure etiology spectrum, its proportions, in the year 2003, chronic nephritis accounted for first, followed by diabetic nephropathy, hypertension. But five years after 2003, the cause of renal failure patients constitute undergone great changes, diabetic nephropathy accounted for first place, followed by chronic nephritis, hypertension. Consider the following reasons: ① incidence of diabetes increased significantly in recent years. ② aging population increasingly worse, to a certain extent, but also enhance the prevalence of diabetic nephropathy. ③ the level of economic development of the region concerned.

Following the adoption of the above description, Jingdong Sino-US Hospital experts say, it is worth noting that the proportion of ischemic kidney disease (CIRD) was also significantly higher (increased to 11.11% from 4.76%). Elderly CIRD most common cause of atherosclerotic renal artery stenosis (ARAS), many studies have confirmed, ARAS prevalence increases with age and there is an increasing trend. Type 2 diabetes patients with renal artery stenosis higher incidence than the general population and more likely to involve kidneys. In recent years, domestic data also showed that with age, ARAS prevalence rate increased.

There is, we can through the contents of the above articles to that in recent years the cause of renal failure in the elderly constitute a large change. Diabetic nephropathy and CIRD were significantly higher percentage, which is closely related to the recent metabolic diseases (mainly diabetes) increased incidence. Limitation of this study is that the sample size is still small, limited its representation, but we still see the trend CRF etiology constituted. Therefore, strengthening the prevention and treatment of metabolic diseases, in order to effectively reduce the incidence of elderly CRF.

Knowledge about the elderly renal failure, summary, for the elderly suffering from renal failure this case, whether the patient has learned a lot of parents some useful knowledge.

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Renal failure in several type?

Renal failure in several type? It can be divided into two types, both of which are specific etiology, clinical manifestations are different, so the treatment will be different.

Renal failure in several type? It divided its Jihuan episodes of acute and chronic.

Renal Failure: Due to a variety of diseases resulting in the loss of two renal excretory function in a short time. Referred to acute renal failure. Expressed as oliguria (urine output <400mL / d) or no urine (urine output <50mL / d), electrolyte and acid-base balance and flash uremia occurred, there was nonoliguric person (urine output> 1000mL / d). Timely treatment, appropriate recovery of renal function. Complex disease, or treatment of critically ill patients is not the time to become chronic renal insufficiency or death. Expert Answers renal failure as follows:

Acute renal failure include the following three cases: ① pre-renal azotemia. Since hypovolemia or cardiac dysfunction resulting in insufficient blood perfusion of renal glomerular filtration rate due. ② renal azotemia. Because of stones, tumors or an enlarged prostate cause acute urinary tract obstruction, resulting in oliguria and blood urea nitrogen (Bun) increased. ③ renal acute renal failure. Because renal disorders caused by severe acute glomerular disease found among acute interstitial - tubule disorders, acute tubular necrosis, acute renal vascular disease and chronic kidney disease, and in some incentive for action so that the two sharp worsening of renal function to see the most acute tubular necrosis.

Chronic renal failure: from a variety of causes of chronic kidney disease due to the development of integrated permits a group of clinical symptoms until the late emergence of the composition. According to the degree of renal dysfunction in chronic renal failure will be divided into four: ① renal function decline reserve, asymptomatic patients. ② renal insufficiency decompensated. ③ renal decompensation (azotemia), patients with fatigue, loss of appetite and anemia. ④ uremia stage, there are symptoms of uremia.


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Help kidney failure patients with medication seven methods

Help kidney failure patients with medication seven ways? Renal failure refers to kidney function partly or total loss of the pathological state. Renal failure is divided into renal failure and chronic renal failure. Due to changes in renal function may lead to changes in pharmacokinetics and pharmacodynamics, and therefore, when the decline in renal function following principles should be applied in the drug master: Your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

① understand commonly used drugs pharmacokinetic and pharmacodynamic characteristics, when necessary, carefully read the package insert or the Clinical Pharmacology monograph; your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

② careful understanding of renal function and other pathophysiological conditions (such as liver function, serum protein levels, acid-base balance and electrolyte metabolism etc.) patient; your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

③ familiar with renal insufficiency and other pathophysiological condition treatment methods, the first choice in renal toxicity of drugs is relatively small; your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!

④ if it proves necessary to apply some nephrotoxic drugs should reduce the dose according to the appropriate method, or extend the dosing interval;

⑤ certain therapeutic window (refer effective concentration range below toxic concentration) is relatively narrow drug, if the conditions can be measured in serum or plasma concentration of the drug (such as digoxin, theophylline, phenytoin sodium amide aminoglycoside antibiotics);

⑥ degree of renal dysfunction should adjust the dose of certain drugs in particular is the prototype by renal excretion of the drug, personalized medicine. Note that drug interactions;

⑦ careful clinical observation, to discover some of the adverse reactions, appropriate treatment promptly.

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Hypertensive renal failure (cell therapy) stage and symptoms?

Stage renal failure and hypertension What are the symptoms? Under normal circumstances, hypertensive renal disease patients is needed to detect and give a treatment of disease. Because without it, it is because this disease if treatment is not timely, then, is likely to continue, so that when re-treatment will be a difficult.

I. First of all, everyone is the initial presentation of symptoms of hypertension renal failure, experts say the medical profession, patients in this period did not have any obvious symptoms manifested renal dysfunction of its damage only through clinical laboratory tests before discovery. Thus, patients with kidney failure are often unclear early hypertensive disease itself or they can not be seriously, thus delaying the best time for treatment of hypertension renal failure.

Second, the symptoms of mild to moderate hypertension renal failure, for this is the period of the disease, also necessary to look for. Progression of the disease in patients with mild to severe, even though their blood human metabolic wastes such as urea increase, but clinically may only have mild symptoms. In this stage the patient, since the kidneys night can not be the same as the daily as to absorb moisture from urine and concentrated, and therefore, in terms of the patient in this stage, there may be more cases of nocturnal polyuria, resulting in a total amount of urine increase. Conversely, due to the high blood pressure in patients with renal failure, so the majority of renal fibrosis has occurred, the number of units remaining normal kidney has been very little, the kidneys can not be discharged too much salt and water, which will make blood pressure more increased. Thus, both high blood pressure and kidney failure will form a vicious cycle chain, promote each other and increased blood pressure in patients with renal disease.

Third, the symptoms of advanced stages of hypertension renal failure, under normal circumstances, we need to know the condition of their patients with the disease has been increasing, to the advanced stage, the patient body in the blood of metabolic waste piled up, the human body Harmful substances will affect the patient's muscles, nerves, digestive tract, brain, skin and other major body systems, causing the patient a series of clinical symptoms, such as muscle twitching, muscle weakness, muscle cramps, needle-like hands and feet pain, nausea, vomiting, loss of appetite, bad breath, anemia, weight loss, skin tan, the skin surface with white powder, body itching, convulsions, and so on. In this case, the patient deterioration developed into uremia, a huge difficulty and risk for post treatment.

Stage renal failure and hypertension What are the symptoms? In summary, it can be seen in different periods exhibited renal hypertension symptoms are different, so the discovery of these conditions, when we need to pay attention, and to go to the hospital identify the cause.



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Elderly kidney failure how else?

Elderly kidney failure how else? Elderly suffering from the disease will be based on the symptoms for kidney failure treatment, but also for the disease complications should also be understood that in order to truly cure the disease.

(A) clinical symptoms

History is not typical elderly renal failure can not clear progression occult, clinical often fatigue, anorexia, nausea, vomiting and other gastrointestinal symptoms to seek treatment, severe mouth of urine, and even gastrointestinal bleeding. Poor, insomnia, difficulty concentrating are common psychiatric symptoms of early disease. Personality changes late disease: depression, memory loss, an error of judgment, indifferent reaction to the outside world. Uremia often have mental disorders, hallucinations, coma, increased neuromuscular excitability often arise, including hiccups, muscle spasms. Renal failure, often late peripheral neuropathy, lower extremity deep section appears strange feeling and was ant-aliasing or tingling, called restless leg syndrome.

(B) complications

Hypertension is a common complication of renal failure, if not timely and effective control of blood pressure can also increase renal damage, creating a vicious cycle. Other cardiovascular complications include pericarditis, cardiomyopathy, heart failure. About 50% of the patients died and cardiovascular complications. Elderly often accompanied by anemia, renal failure, anemia is associated with symptoms of uremia. Anemia can make heart failure and angina symptoms worse. Anemia related to kidney mechanism is controversial, in addition to a variety of factors cause kidney produce insufficient erythropoietin factor, the uremic plasma of some toxic substances also interfere with erythropoiesis and metabolism. Generally considered to be caused by multiple factors obstacle. Suffering from the disease can occur when water and electrolyte imbalance and metabolic disorders, hyponatremia, hyperkalemia, calcium and phosphorus metabolism imbalance (renal dystrophy syndrome), low blood sugar and high blood sugar and so on, if you can not get timely treatment It can be a cause of death of the patient.

Above for the elderly renal failure related content to do a presentation, hoping to help the elderly. There are a variety of clinical symptoms of the disease, but also a lot of complications, so the treatment method to be correct.


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How stage chronic renal failure?

How stage chronic renal failure? Case of chronic renal failure stage is carried out? According to the severity of stage. Generally can be divided into four phases in clinical, each treatment is not the same.

Chronic renal failure refers to kidney disease or chronic kidney diseases involving the kidney caused by systemic loss, as well as a variety of clinical symptoms and the resulting metabolic disorders consisting syndrome. In a few cases, chronic renal failure may also be transformed from acute renal failure from. We will now be described with chronic renal failure in clinical staging. So as to obtain treatment for kidney failure. Chronic renal failure

(1) decompensated chronic renal failure (renal decrease of reserve capacity): patients without kidney failure symptoms. Serum creatinine <133 u m01 / L; GFR (glomerular filtration rate) 50-80 ml / min.

(2) chronic renal failure decompensation (azotemia): renal failure early, patients are usually no obvious symptoms, may have mild anemia, polyuria, and nocturia increased: serum creatinine> 133 μmol / L, but <450 μmol / L: GFR (glomerular filtration rate) 25-50 ml / min.

(3) chronic renal failure decompensation late (stage renal failure): anemia in patients with obvious, nocturia and water, electrolyte imbalance, and may have mild gastrointestinal, cardiovascular and central nervous system symptoms; serum creatinine It was significantly higher (approximately 450-707 u mol / L); GFR (glomerular filtration rate) 10-25 ml / min.

(4) end-stage chronic renal failure (uremia): advanced renal failure, renal failure and clinical manifestations of blood biochemical abnormalities have been very significant, uremia syndrome group, each severe symptoms, especially stomach intestinal, cardiovascular, and neurological symptoms more prominent. Water, electrolyte imbalance serious, often have significant metabolic acidosis, serum creatinine greater than 707 u mol / L: GFR (glomerular filtration rate) of less than 10 ml / min.

Stage chronic renal failure is helpful for the treatment, can make the appropriate treatment according to the disease in different periods. This species is more likely in early treatment, once inside there are some difficulties in the late treatment.


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Chronic renal failure how care?

Chronic renal failure how care? Chronic renal failure care knowledge is very important for all of us, the main control points can be, one of its nursing problems, the second is nursing. Together with the treatment can cure this disease.

Although multiple renal failure treatment, but depending on the type of treatment required. For chronic kidney disease, the two-thirds rule seven support, here is easy to see with chronic renal failure care more important. Specific look.

(A) major chronic renal failure nursing problems:

1. Fluid overload - and salt, excessive fluid intake related. 2. Potential complications: stroke volume reduction. 3. infection - and leukopenia cause a decline in immunity. 4. Risk of injury - related hypertension or renal osteodystrophy. 5. impaired skin integrity is dangerous - stage renal disease and edema caused by related. 6. Lack of knowledge - and do not understand the disease processes.

(B) Chronic renal failure care measures:

1. Diet Care: limit the intake of protein, reduce the symptoms of uremia, but sufficient heat should be supplied to the patient in order to reduce the consumption of protein.

2. reduce edema: regular measurement of body weight daily, accurate records of intake fluid volume, and strictly control the amount of fluid.

3. Ensure rest: bed rest, avoid over exertion.

4. Prevention of infection: ward regularly ventilation and air disinfection, strict aseptic technique. Enhance life care, patient education away from public places. Prescribed medication such as skin itching, avoid scratching.

5. discharge guidance: periodic review of renal function, serum electrolytes, etc., accurate records of daily urine output.


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2015年12月26日星期六

Chronic renal failure, which can cause kidney changes

The occurrence and development of chronic renal failure can occur a series of compensatory response structure and function of the kidneys, in order to make the body adapt to the body due to the reduced number of units of renal function caused by various changes, maintain the balance of the body. These compensatory response of the structure and function mainly includes the following aspects:

① increase in residual nephrons glomerular filtration rate, action to compensate for the loss of function of the nephron, the body excrete metabolic waste, but residual renal units due to the load increase, and further accelerate the glomerular damage, such as causing kidney pellets hypertrophy;

② compensatory glomerular hypertrophy, although no adverse reactions in intact nephrons, but also can enhance renal function, but in the glomerular diseases can cause decreased glomerular filtration rate secondary, accelerated glomerular hardening;

③ glomerular and interstitial inflammatory cell infiltration, can swallow, remove cause glomerular and tubular lesions harmful substances, but can also release growth factors and inflammatory mediators, stimulate collagen deposition and mesangial matrix increase, leading to renal Ball sclerosis and interstitial fibrosis occurs in renal;

④ increase in residual renal sodium excretion units can be prevented extracellular fluid expansion and hypertension produce, but can be caused by low sodium intake reduced capacity response;

⑤ renal tubular secretion of ammonia increased, although you can reduce the production of acid poisoning, but accelerated tubulointerstitial damage;

⑥ urinary protein excretion may lead to patient edema, hypoalbuminemia, and accelerate renal tubular glomerular damage;

⑦ secondary hyperparathyroidism, so that the body increases the excretion of phosphorus, reducing the phosphorus retention, but its consequences are caused disorder and imbalance uremic bone disease and other organ function.

Thus, compensatory response in chronic renal failure occurred during a series of kidney structure and function, although you can partially corrected nephron loss resulting from a series of pathophysiological changes, but if you do not artificially be actively controlled, They are likely to have adverse effects to the body, can eventually lead to glomerulosclerosis and tubulointerstitial damage.

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Stage renal failure (cell therapy) symptoms

What are the symptoms of advanced renal failure is? Kidney function if not properly managed, will be accompanied by the development of advanced renal failure, which is usually what people say uremia, but at this point sharp pressure patients do not be too large, otherwise it will increase the development of the disease, advanced kidney failure in clinical practice will be mainly in the following aspects of performance:

(1) of the hematopoietic system symptoms: chronic renal failure patients have varying severity of anemia, caused by poor long-term nutrition, erythropoietin reduce hemolysis and renal failure due to many patients with bleeding tendency, symptoms of subcutaneous bleeding, stasis. plaque, gingival bleeding, epistaxis, severe gastrointestinal bleeding may erupt and death. In addition, there are white blood cells it can be very, due to "uremic toxins" to do with, so that the formation and function of white blood cells are obstacles, WBC whereabouts (including mainly to decreased production of lymphocytes), neutrophil chemotaxis, phagocytosis, and the ability to kill bacteria also drop dead dwarf.

(2) digestive symptoms: digestive symptoms are the earliest and one of the most common symptoms, mainly anorexia, indigestion, severe cases may have glossitis, mouth fall may have vomiting, if peptic ulcer involving the vascular namely blood.

(3) respiratory symptoms: respiratory system consistent sample, generally when there is acidosis appears breathing hard, but also by the emergence of uremia bronchitis, pneumonia and pleurisy and other symptoms.

(4) the cardiovascular system symptoms: common are hypertension, myocarditis and pericarditis uremic, various arrhythmias and heart failure.

(5) neuropsychiatric symptoms: central repercussions dull symptoms, depression, irritability, agitation, convulsions, lethargy and coma symptoms of peripheral symptoms of peripheral nerve degeneration diseases, skin allergies, burning, tired limbs forces and activities. obstruction and so on.

(6) Skin symptoms: Symptoms of skin can be pale, dull, itching and "urea cream."

(7) The skeletal system symptoms: Because calcium and phosphorus metabolism disorder, may show osteoporosis, osteomalacia or osteitis and appear bitterly pseudo-fracture

Patient treatment at this time do not give up, we must adhere to treatment, and be sure to arrange three meals a day diet program requires that patients do not have too much pressure, as science continues to evolve, the successful introduction of cell transplantation therapy, We have made many kidney failure patients benefit a lot, a lot of quality of life in patients with renal failure has increased, and prolong their lives, so the patient to early treatment using cell transplantation.

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Severe kidney failure do

Renal failure, referred to as "renal failure", as the name suggests is the body's kidney function lesions occurred, there has been failure phenomenon. From a medical perspective, what is it renal failure? Renal failure is the occurrence of renal fibrosis after its function decreased, leading to a variety of metabolic balance of human disorders, the body of the system will be a deterioration of renal function related complications final stage. Based on the clinical onset of renal failure Jihuan divided into two: renal failure and chronic renal failure, while the latter is the most common.

Renal Failure serious? Renal failure is what disease?

Accurately speaking, renal failure is not an independent disease, but the deterioration of the later stages of kidney disease progression. For kidney disease patients, kidney failure is the most unwanted outcome. Why? Renal failure, which means that patients with kidney disease kidneys can not properly work. Under normal circumstances, it exercised mainly kidneys filter the body of metabolic waste and useful material on the human body re-absorption back function. Once the kidneys do not work properly, the body's metabolic waste can not be excreted, while the human intake of nutrients from the diet, but a steady stream of leakage in vitro. Thus, the function of the kidneys can play more small, kidney atrophy increasingly heavy, we can only rely on the blood substitute kidney dialysis machines to work.

Replace kidney function by dialysis treatment the continuation of life, the ultimate outcome of this is carried out in patients with renal failure, kidney function slowly lose, kidneys continue to shrink until complete necrosis, renal failure patients' lives come to an end. As can be seen, the incidence of renal failure for kidney patients is a bad news, one is because the severity of renal failure in patients with nephropathy caused, and secondly because of the renal dialysis treatment can only exercise the embarrassing situation.

Renal Failure serious? What is the treatment process pay attention to?

Dialysis is merely substitute kidney lesions work, to exercise their lesions kidney function, however, there is no effective control of the disease, renal fibrosis Organization will become increasingly large, the normal function of the kidney is a corresponding decline. Dialysis and no real damage to the kidneys play a therapeutic role. Really want to renal failure in patients treated kidney damage, to restore its original kidney function, can only start from the root causes of renal failure occur.

As already described, kidney failure continue to occur because of kidney fibrosis caused by, so I wanted to treat renal fibrosis in kidneys would only have occurred through a means for repair. This effective method must also be able to do, to cause renal fibrosis were cleared. Thus, the function of the kidneys in order to be truly restored, in order to continuously improve renal disease.


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