2016年1月18日星期一

Why chronic renal failure patients will appear on behalf of protein and amino acids

Why chronic renal failure patients may appear protein and amino acid metabolism? Patients with chronic renal failure due to impaired kidney function, proteinuria, there was a series of symptoms and metabolic disorders, metabolic disorders and other amino acids. This health impact on patients is great, toxins and metabolites in the body can not be discharged, the patient prone to self-poisoning phenomenon.

So why is there renal failure patients protein and amino acid metabolism it? Protein metabolism in patients with chronic renal failure have a very important significance. Chronic renal failure patients due to the impact of the disease, caused by loss of appetite. Dietary protein intake is restricted, protein catabolism increase, in vivo loss of large amounts of protein in the urine, often causing hypoalbuminemia occurred. Chronic renal failure patients during dialysis, dialysate protein-losing cause hypoproteinemia more apparent. Due to lack of negative nitrogen balance and daily caloric intake, patients often have muscle wasting and fat tissue reduction, extracellular and total protein were decreased, the absolute value of albumin synthesis and decomposition of decline.

Because patients with renal dysfunction, α2 macroglobulin one, β2 microglobulin, β2-glycoprotein, prealbumin, globulin light chains, as well as protein and so this week raised or appear in serum. Amino acid metabolism disorder, manifested in the plasma, red blood cells and muscle amino acid levels and proportion of ingredients is not normal, mainly for the reduction in the level of essential amino acids, elevated levels of non-essential amino acids. Both ratios decline, may further aggravate hypoproteinemia.

Patients with chronic renal failure due to the impact of the disease, there are a lot of restrictions in the diet, and the patient's appetite is often poor, as well as malignant, vomiting, loss of appetite and other symptoms, the patient likely to cause malnutrition in the body, the body needed lack of timely nutritional supplement, thus creating a vicious cycle.

Therefore, patients with chronic renal failure to pay attention to food supplements contain high quality protein, it is conducive to fully utilize the body's absorption of protein and reduce the production of metabolic waste, but also reduce the burden on the kidneys, help restore the patient's condition.


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