Help kidney failure patients with medication seven ways? Renal failure refers to kidney function partly or total loss of the pathological state. Renal failure is divided into renal failure and chronic renal failure. Due to changes in renal function may lead to changes in pharmacokinetics and pharmacodynamics, and therefore, when the decline in renal function following principles should be applied in the drug master: Your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!
① understand commonly used drugs pharmacokinetic and pharmacodynamic characteristics, when necessary, carefully read the package insert or the Clinical Pharmacology monograph; your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!
② careful understanding of renal function and other pathophysiological conditions (such as liver function, serum protein levels, acid-base balance and electrolyte metabolism etc.) patient; your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!
③ familiar with renal insufficiency and other pathophysiological condition treatment methods, the first choice in renal toxicity of drugs is relatively small; your problem kidney disease experts have to communicate with you by phone. If there are problems can be directly dial the phone or online one free expert advice. We will continue to serve you to answer!
④ if it proves necessary to apply some nephrotoxic drugs should reduce the dose according to the appropriate method, or extend the dosing interval;
⑤ certain therapeutic window (refer effective concentration range below toxic concentration) is relatively narrow drug, if the conditions can be measured in serum or plasma concentration of the drug (such as digoxin, theophylline, phenytoin sodium amide aminoglycoside antibiotics);
⑥ degree of renal dysfunction should adjust the dose of certain drugs in particular is the prototype by renal excretion of the drug, personalized medicine. Note that drug interactions;
⑦ careful clinical observation, to discover some of the adverse reactions, appropriate treatment promptly.
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